Histone H2A antibody

Catalog No. ABIN4889652

Product Details anti-Histone H2A Antibody

Target: Histone H2A

Reactivity: Saccharomyces cerevisiae, Schizosaccharomyces pombe

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: None

Immunogen: This Histone H2A antibody was raised against recombinant yeast histone H2A.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-Histone H2A antibody (ABIN4889652)

Young, Hillyer, Hokamp, Fitzpatrick, Konstantinov, Welty, Ness, Werner-Washburne, Fleming, Osley: "Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast." in: BMC genomics, Vol. 18, Issue 1, pp. 107, (2017) (PubMed).

Ferrari, Bruhn, Peretti, Cassani, Carotenuto, Elgendy, Shubassi, Lucca, Bermejo, Varasi, Minucci, Longhese, Foiani: "PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response." in: Molecular cell, Vol. 67, Issue 2, pp. 266-281.e4, (2017) (PubMed).

Fleming, Beggs, Church, Tsukihashi, Pennings: "The yeast Cyc8-Tup1 complex cooperates with Hda1p and Rpd3p histone deacetylases to robustly repress transcription of the subtelomeric FLO1 gene." in: Biochimica et biophysica acta, Vol. 1839, Issue 11, pp. 1242-55, (2014) (PubMed).

Bandhu, Kang, Fukunaga, Goto, Sugimoto: "Ddc2 mediates Mec1 activation through a Ddc1- or Dpb11-independent mechanism." in: PLoS genetics, Vol. 10, Issue 2, pp. e1004136, (2014) (PubMed).

Tessarz, Santos-Rosa, Robson, Sylvestersen, Nelson, Nielsen, Kouzarides: "Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification." in: Nature, Vol. 505, Issue 7484, pp. 564-8, (2014) (PubMed).

Jha, Strahl: "An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair." in: Nature communications, Vol. 5, pp. 3965, (2014) (PubMed).

Limbo, Moiani, Kertokalio, Wyman, Tainer, Russell: "Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair." in: Nucleic acids research, Vol. 40, Issue 22, pp. 11435-49, (2012) (PubMed).

Andrews, Chen, Zevin, Stargell, Luger: "The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions." in: Molecular cell, Vol. 37, Issue 6, pp. 834-42, (2010) (PubMed).

Target Details for Histone H2A

Target: Histone H2A

Abstract: Histone H2A Products

Synonyms: 5499 antibody, CG5499 antibody, Dmel\\CG5499 antibody, H2A antibody, H2A.F/Z antibody, H2A.X antibody, H2A.Z antibody, H2AV antibody, H2AV_DROM antibody, H2AX antibody, H2AZ antibody, H2Av antibody, H2AvD antibody, H2a.V antibody, H2av antibody, H2avD antibody, HIS antibody, HIS2AV antibody, HIS2AVD antibody, His antibody, His2 antibody, His2AV antibody, His2AvD antibody, HisH2Av antibody, Hist antibody, Hist2av antibody, gamma-H2Av antibody, gamma-HIS2AV antibody, gamma-His2Av antibody, gammaH2Av antibody, h2AvD antibody, his antibody, l(3)05146 antibody, l(3)810 antibody, l(3)97Dd antibody, l(3)L1602 antibody, DDBDRAFT_0205974 antibody, DDBDRAFT_0216271 antibody, DDB_0205974 antibody, DDB_0216271 antibody, RGD1564767 antibody, H2a-221 antibody, H2A-III antibody, HIST1H2AA antibody, Histone H2A variant antibody, putative histone H2A antibody, histone H2A antibody, histone cluster 1 H2A family member F antibody, histone H2A-like antibody, histone cluster 1, H2af antibody, histone2A1 antibody, histone cluster 1, H2A, III antibody, histone cluster 1, H2ac antibody, His2Av antibody, LMJF_17_0280 antibody, H2AX antibody, Hist1h2af antibody, LOC100425378 antibody, his2a1 antibody, HIST1H2A3 antibody, HIST1H2AC antibody, h2a-A antibody

Molecular Weight: 14 kDa