TNFRSF18 antibody (Tumor Necrosis Factor Receptor Superfamily, Member 18) (AA 26-161) (APC)

Details for Product anti-TNFRSF18 Antibody No. ABIN4896942, Supplier: Log in to see
Antigen
  • GITR
  • TNFRSF18
  • AITR
  • Gitr
  • CD357
  • GITR-D
  • TNF receptor superfamily member 18
  • tumor necrosis factor receptor superfamily, member 18
  • TNFRSF18
  • Tnfrsf18
Epitope
AA 26-161, Thr43Ala-Mutant
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15
10
7
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3
2
2
1
1
1
1
1
1
Reactivity
Human
176
141
17
Host
Mouse
164
91
39
1
Clonality (Clone)
Monoclonal ()
Conjugate
This TNFRSF18 antibody is conjugated to APC
23
21
19
16
7
7
5
5
5
5
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3
3
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
191
78
72
56
30
20
13
7
5
5
4
3
3
2
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Mouse myeloma cell line NS0-derived recombinant human GITR/TNFRSF18, Gln26-Glu161 (Thr43Ala), Accession # Q9Y5U5
Clone 110416
Isotype IgG1
Specificity Detects human GITR in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) 4-1BB, recombinant mouse (rm) 4-1BB, rhCD27, rmCD27, rhCD30, rmCD30, rhCD40, rmCD40, rhDR3, rhDR6, rhEDAR, rmEDAR, rhFas, rmFAS, rmGITR, rhHVEM, rhLymphotoxin R beta , rmLymphotoxin R beta , rhNGF R, rhOPG, rmOPG, rhRANK, rmRANK, rhTAJ, rhTNF RI, rmTNF RI, rhTNF RII, or rmTNF RII.
Purification Protein A or G purified from hybridoma culture supernatant
Plasmids, Primers & others Plasmids, Primers & others TNFRSF18 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name GITR/TNFRSF18 (TNFRSF18 Antibody Abstract)
Background Alternative Names: Activation-inducible TNFR family receptor, AITR, AITRTNF receptor superfamily activation-inducible protein, CD357, CD357 antigen, GITR-D, GITRtumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, TNFRSF18, tumor necrosis factor receptor superfamily, member 18
Gene ID 8784
UniProt Q9Y5U5
Application Notes Flow Cytometry 10 uL/10^6 cells
Restrictions For Research Use only
Format Liquid
Buffer Supplied in a saline solution containing BSA and Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Protect from light. Do not freeze. 12 months from date of receipt,2°C to 8°C as supplied.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-161), (Thr43Ala-Mutant) antibody (APC) (ABIN4896942) Detection of GITR/TNFRSF18 in Human Blood CD4+ Lymphocytes by Flow Cytometry. Human p...
Product cited in: Tuyaerts, Van Meirvenne, Bonehill, Heirman, Corthals, Waldmann, Breckpot, Thielemans, Aerts: "Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells." in: Journal of leukocyte biology, Vol. 82, Issue 1, pp. 93-105, 2007 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Perez, Karamouzis, Skarlos, Ardavanis, Sotiriadou, Iliopoulou, Salagianni, Orphanos, Baxevanis, Rigatos, Papamichail: "CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 9, pp. 2714-21, 2007 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Yang, Yamagiwa, Ichida, Matsuda, Sugahara, Watanabe, Sato, Abo, Horwitz, Aoyagi: "Increase of CD4+ CD25+ regulatory T-cells in the liver of patients with hepatocellular carcinoma." in: Journal of hepatology, Vol. 45, Issue 2, pp. 254-62, 2006 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

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