TNFRSF10B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10b) (AA 56-182) (PE)

Details for Product anti-TNFRSF10B Antibody No. ABIN4898055, Supplier: Log in to see
Antigen
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Alternatives
anti-Human TNFRSF10B antibody for Flow Cytometry
Epitope
AA 56-182
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Reactivity
Human
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2
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Host
Mouse
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Clonality (Clone)
Monoclonal ()
Conjugate
This TNFRSF10B antibody is conjugated to PE
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Application
Flow Cytometry (FACS)
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14
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Options
Supplier
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Supplier Product No.
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Immunogen Mouse myeloma cell line NS0-derived recombinant human TRAIL R2/TNFRSF10B, Ile56-Glu182, Accession # O14763
Clone 71908
Isotype IgG2b
Specificity Detects human TRAIL R2 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) TRAIL R1, rhTRAIL R3, rhTRAIL R4, or recombinant mouse TRAIL R2.
Purification Protein A or G purified from hybridoma culture supernatant
Plasmids, Primers & others Plasmids, Primers & others TNFRSF10B products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TRAIL R2/TNFRSF10B (TNFRSF10B Antibody Abstract)
Background Alternative Names: CD262, CD262 antigen, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAILR2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9
Gene ID 8795
UniProt O14763
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
Application Notes Flow Cytometry 10 uL/10^6 cells
Restrictions For Research Use only
Format Liquid
Buffer Supplied in a saline solution containing BSA and Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Protect from light. Do not freeze. 12 months from date of receipt,2°C to 8°C as supplied.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-182) antibody (PE) (ABIN4898055) MDA-MB-231 Human Cell Line by Flow Cytometry. MDA-MB-231 human breast cancer cell lin...
Product cited in: Warat, Sadowski, Szliszka, Król, Czuba: "The role of selected flavonols in tumor necrosis factor-related apoptosis-inducing ligand receptor-1 (TRAIL-R1) expression on activated RAW 264.7 macrophages." in: Molecules (Basel, Switzerland), Vol. 20, Issue 1, pp. 900-12, 2015 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Kim, Woo, Jeong, Ryu, Jang, Jeun: "Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma." in: Stem cells translational medicine, Vol. 3, Issue 2, pp. 172-82, 2014 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Peppa, Gill, Reynolds, Easom, Pallett, Schurich, Micco, Nebbia, Singh, Adams, Kennedy, Maini: "Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion." in: The Journal of experimental medicine, Vol. 210, Issue 1, pp. 99-114, 2013 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Gupta, Francis, Nair, Mo, Aggarwal et al.: "Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 ..." in: The Journal of biological chemistry, Vol. 288, Issue 45, pp. 32343-56, 2013 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Gojo, Tan, Fang, Sadowska, Lapidus, Baer, Carrier, Beumer, Anyang, Srivastava, Espinoza-Delgado, Ross: "Translational phase I trial of vorinostat (suberoylanilide hydroxamic acid) combined with cytarabine and etoposide in patients with relapsed, refractory, or high-risk acute myeloid leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 7, pp. 1838-51, 2013 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Hong, Kim, Kim, Ha, Kim, Bae, Kim, Lee, Kim: "Smad7 protein induces interferon regulatory factor 1-dependent transcriptional activation of caspase 8 to restore tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis." in: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 3560-70, 2013 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Kalb, Glaser, Stary, Koszik, Stingl: "TRAIL(+) human plasmacytoid dendritic cells kill tumor cells in vitro: mechanisms of imiquimod- and IFN-?-mediated antitumor reactivity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 4, pp. 1583-91, 2012 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Kang, Chen, Yu, Li, Sun, Zhang, Cao: "Drozitumab, a human antibody to death receptor 5, has potent antitumor activity against rhabdomyosarcoma with the expression of caspase-8 predictive of response." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 10, pp. 3181-92, 2011 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Szliszka, Helewski, Mizgala, Krol: "The dietary flavonol fisetin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells." in: International journal of oncology, Vol. 39, Issue 4, pp. 771-9, 2011 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Secchiero, Melloni, Corallini, Beltrami, Alviano, Milani, DAurizio, di Iasio, Cesselli, Bagnara, Zauli: "Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells." in: Stem cells (Dayton, Ohio), Vol. 26, Issue 11, pp. 2955-63, 2008 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Kim, Lim, Park, Jeong, Oh, Jeong, Oh, Park, Sung, Jeun: "Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma." in: Cancer research, Vol. 68, Issue 23, pp. 9614-23, 2008 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Wu, Kao, Safa: "TRAIL recombinant adenovirus triggers robust apoptosis in multidrug-resistant HL-60/Vinc cells preferentially through death receptor DR5." in: Human gene therapy, Vol. 19, Issue 7, pp. 731-43, 2008 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Dunn, Brunetto, Reynolds, Christophides, Kennedy, Lampertico, Das, Lopes, Borrow, Williams, Humphreys, Afford, Adams, Bertoletti, Maini: "Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage." in: The Journal of experimental medicine, Vol. 204, Issue 3, pp. 667-80, 2007 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

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