CXCR6 antibody (Chemokine (C-X-C Motif) Receptor 6) (AA 1-342)

Details for Product anti-CXCR6 Antibody No. ABIN4899064, Supplier: Log in to see
Antigen
  • BONZO
  • CD186
  • STRL33
  • TYMSTR
  • BB217514
  • C-X-C motif chemokine receptor 6
  • chemokine (C-X-C motif) receptor 6 L homeolog
  • chemokine (C-X-C motif) receptor 6
  • CXCR6
  • cxcr6.L
  • Cxcr6
Epitope
AA 1-342
35
25
16
15
11
10
7
7
5
3
2
2
2
2
2
2
1
1
Reactivity
Human
186
66
43
11
3
3
Host
Mouse
116
72
36
18
Clonality (Clone)
Monoclonal ()
Conjugate
This CXCR6 antibody is un-conjugated
10
9
9
8
7
7
7
7
6
6
6
6
6
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS)
112
95
53
48
46
17
13
12
8
3
3
2
1
Options
Supplier
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Supplier Product No.
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Immunogen NS0 mouse myeloma cell line transfected with human CXCR6, Met1-Leu342, Accession # O00574
Clone 56811
Isotype IgG2b
Specificity Stains human CXCR6 transfectants but not irrelevant transfectants.
Characteristics Clone 56811 was used by HLDA to establish CD designation
Purification Protein A or G purified from ascites
Sterility 0.2 μm filtered
Plasmids, Primers & others Plasmids, Primers & others CXCR6 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CXCR6 (CXCR6 Antibody Abstract)
Background Alternative Names: Bonzo, BONZOG-protein coupled receptor bonzo, CD186, CD186 antigen, CDw186, chemokine (C-X-C motif) receptor 6, C-X-C chemokine receptor type 6, CXCR6, CXC-R6, CXCR-6, G protein-coupled receptor, STRL33, STRL33G-protein coupled receptor STRL33, TYMSTRCD186
Gene ID 10663
UniProt O00574
Application Notes Flow Cytometry 2.5 μg/10^6 cells
CyTOF-reported
Restrictions For Research Use only
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) antibody (ABIN4899064) Detection of CXCR6 in Human PBMCs by Flow Cytometry. Human peripheral blood mononucle...
Flow Cytometry (FACS) image for anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) antibody (ABIN4899064) Detection of CXCR6 in HEK293 Human cell line transfected with Human CXCR6 and eGFP by...
Product cited in: Pacheco-Rodriguez, Kumaki, Steagall, Zhang, Ikeda, Lin, Billings, Moss: "Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1270-7, 2009 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Gaida, Günther, Wagner, Friess, Giese, Schmidt, Hänsch, Wente: "Expression of the CXCR6 on polymorphonuclear neutrophils in pancreatic carcinoma and in acute, localized bacterial infections." in: Clinical and experimental immunology, Vol. 154, Issue 2, pp. 216-23, 2008 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Wente, Gaida, Mayer, Michalski, Haag, Giese, Felix, Bergmann, Giese, Friess: "Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma." in: International journal of oncology, Vol. 33, Issue 2, pp. 297-308, 2008 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Held-Feindt, Rehmke, Mentlein, Hattermann, Knerlich, Hugo, Ludwig, Mehdorn: "Overexpression of CXCL16 and its receptor CXCR6/Bonzo promotes growth of human schwannomas." in: Glia, Vol. 56, Issue 7, pp. 764-74, 2008 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Zola, Swart, Banham, Barry, Beare, Bensussan, Boumsell, D Buckley, Bühring, Clark, Engel, Fox, Jin, Macardle, Malavasi, Mason, Stockinger, Yang: "CD molecules 2006--human cell differentiation molecules." in: Journal of immunological methods, Vol. 319, Issue 1-2, pp. 1-5, 2007 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Kang, Lim, Andrisani, Broxmeyer, Kim: "Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3724-33, 2007 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Facco, Baesso, Miorin, Bortoli, Cabrelle, Boscaro, Gurrieri, Trentin, Zambello, Calabrese, Cassatella, Semenzato, Agostini: "Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis." in: Journal of leukocyte biology, Vol. 82, Issue 4, pp. 946-55, 2007 (PubMed). Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Human).

Patel, Bailey, Gresham, Schuchman, Shelhamer, Goldstein, Foxwell, Stemerman, Maranchie, Valente, Mummidi, Chandrasekar: "TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells." in: Biochemical and biophysical research communications, Vol. 347, Issue 4, pp. 1113-20, 2006 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Hirahara, Liu, Clark, Yamanaka, Fuhlbrigge, Kupper: "The majority of human peripheral blood CD4+CD25highFoxp3+ regulatory T cells bear functional skin-homing receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 7, pp. 4488-94, 2006 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ruth, Haas, Park, Amin, Martinez, Haines, Shahrara, Campbell, Koch: "CXCL16-mediated cell recruitment to rheumatoid arthritis synovial tissue and murine lymph nodes is dependent upon the MAPK pathway." in: Arthritis and rheumatism, Vol. 54, Issue 3, pp. 765-78, 2006 (PubMed). Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Annels, Willemze, van der Velden, Faaij, van Wering, Sie-Go, Egeler, van Tol, Révész: "Possible link between unique chemokine and homing receptor expression at diagnosis and relapse location in a patient with childhood T-ALL." in: Blood, Vol. 103, Issue 7, pp. 2806-8, 2004 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Lim, Hillsamer, Kim: "Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses." in: The Journal of clinical investigation, Vol. 114, Issue 11, pp. 1640-9, 2004 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

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