CCR4 antibody (Chemokine (C-C Motif) Receptor 4) (AA 1-360)

Details for Product anti-CCR4 Antibody No. ABIN4899090, Supplier: Log in to see
Antigen
  • CC-CKR-4
  • CD194
  • CKR4
  • CMKBR4
  • ChemR13
  • HGCN:14099
  • K5-5
  • Ccr4
  • C-C CKR-4
  • CHEMR1
  • Cmkbr4
  • LESTR
  • Sdf1r
  • C-C motif chemokine receptor 4
  • chemokine (C-C motif) receptor 4
  • CCR4
  • Ccr4
Epitope
AA 1-360
24
15
15
15
12
9
7
6
5
4
4
4
3
3
2
2
2
2
1
1
1
1
Reactivity
Human
191
66
45
9
8
6
3
2
2
Host
Mouse
124
66
18
9
Clonality (Clone)
Monoclonal ()
Conjugate
This CCR4 antibody is un-conjugated
10
8
8
8
7
4
4
4
4
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS)
92
83
72
41
38
15
14
9
8
6
6
5
4
4
3
3
3
2
1
Options
Supplier
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Supplier Product No.
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Immunogen Human CCR4 transfectants, Met1-Leu360, Accession # P51679
Clone 205410
Isotype IgG2b
Specificity Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects CCR4 on human PBLs and platelets.
Characteristics Clone 205410 was used by HLDA to establish CD designation
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Plasmids, Primers & others Plasmids, Primers & others CCR4 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CCR4 (CCR4 Antibody Abstract)
Background Alternative Names: C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4HGCN:14099, CCR-4, CD194, CD194 antigen, chemokine (C-C motif) receptor 4, chemokine (C-C) receptor 4, ChemR13, CKR4MGC88293, CMKBR4k5-5, K5-5
Gene ID 1233
UniProt P51679
Application Notes Flow Cytometry 0.25 μg/10^6 cells
CyTOF-reported
Restrictions For Research Use only
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 1-360) antibody (ABIN4899090) Detection of CCR4 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclea...
Product cited in: Aruga, Takeshita, Kotera, Okuyama, Matsushita, Ohta, Takeda, Yamamoto: "Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 8, pp. 2224-31, 2013 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Islam, Chang, Colvin, Byrne, McCully, Moser, Lira, Charo, Luster: "Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells." in: Nature immunology, Vol. 12, Issue 2, pp. 167-77, 2011 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Pandya, Al-Jaderi, Høglund, Holmøy, Harbo, Norgauer, Maghazachi: "Identification of human NK17/NK1 cells." in: PLoS ONE, Vol. 6, Issue 10, pp. e26780, 2011 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Fifadara, Aye, Raghuwanshi, Richardson, Ono: "CCR1 expression and signal transduction by murine BMMC results in secretion of TNF-alpha, TGFbeta-1 and IL-6." in: International immunology, Vol. 21, Issue 8, pp. 991-1001, 2009 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Nakamura, Jo, Tabata, Ishikawa: "Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (Alopecia Areata) in a C3H/HeJ mouse model." in: The American journal of pathology, Vol. 172, Issue 3, pp. 650-8, 2008 (PubMed). Method employed by authors: Immunohistochemistry (IHC) (Sample species: Human).

Zola, Swart, Banham, Barry, Beare, Bensussan, Boumsell, D Buckley, Bühring, Clark, Engel, Fox, Jin, Macardle, Malavasi, Mason, Stockinger, Yang: "CD molecules 2006--human cell differentiation molecules." in: Journal of immunological methods, Vol. 319, Issue 1-2, pp. 1-5, 2007 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ponte, Marais, Gallay, Langonné, Delorme, Hérault, Charbord, Domenech: "The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 7, pp. 1737-45, 2007 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Kang, Lim, Andrisani, Broxmeyer, Kim: "Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3724-33, 2007 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Marchal-Sommé, Uzunhan, Marchand-Adam, Valeyre, Soumelis, Crestani, Soler: "Cutting edge: nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 10, pp. 5735-9, 2006 (PubMed). Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Human).

Gounni Abdelilah, Wellemans, Agouli, Guenounou, Hamid, Beck, Lamkhioued: "Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines." in: Clinical immunology (Orlando, Fla.), Vol. 120, Issue 2, pp. 220-31, 2006 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Nakayama, Tanaka, Nagai, Iwamoto, Shioda: "A CCR2-V64I polymorphism affects stability of CCR2A isoform." in: AIDS, Vol. 18, Issue 5, pp. 729-38, 2004 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ohshima, Karube, Kawano, Tsuchiya, Suefuji, Yamaguchi, Suzumiya, Kikuchii: "Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis." in: International journal of oncology, Vol. 25, Issue 3, pp. 605-13, 2004 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

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