CRLF2 antibody (Cytokine Receptor-Like Factor 2) (AA 20-233)

Details for Product anti-CRLF2 Antibody No. ABIN4899486
Antigen
  • CRLF2
  • CRL2
  • CRLF2Y
  • TSLPR
  • CRLM2
  • Ly114
  • Tpte2
  • Tslpr
  • Crl2
  • cytokine receptor like factor 2
  • cytokine receptor-like factor 2
  • CRLF2
  • Crlf2
Epitope
AA 20-233
5
5
4
4
2
2
2
2
2
1
1
1
1
Reactivity
Mouse (Murine)
75
33
23
Host
Goat
78
19
3
Clonality
Polyclonal
Conjugate
This CRLF2 antibody is un-conjugated
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
55
30
26
15
15
6
5
2
2
1
Options
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse TSLP R, Ala20-Leu233, Accession # BAA92159
Isotype IgG
Specificity Detects mouse TSLP R in direct ELISAs and Western blots.
Purification Immunogen affinity purified
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Plasmids, Primers & others Plasmids, Primers & others CRLF2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TSLP R (CRLF2 Antibody Abstract)
Background Alternative Names: CRL2, CRL2cytokine receptor CRL2 precusor, CRLF2, CRLF2Y, CRLM-2, Cytokine receptor-like 2, cytokine receptor-like factor 2, ILXR, IL-XR, P2RY8/CRLF2 fusion, PCOR1, Thymic stromal lymphopoietin protein receptor, thymic stromal lymphopoietin receptor, thymic stromal-derived lymphopoietin receptor, TSLP receptor, TSLPR
Gene ID 64109
Application Notes Western Blot 0.1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
Neutralization 0.2-0.6 μg/mL
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 20-233) antibody (ABIN4899486) Detection of TSLP R in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were st...
Neutralization (Neut) image for anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 20-233) antibody (ABIN4899486) Cell Proliferation Induced by TSLP and Neutralization by Mouse TSLP R Antibody. Recom...
Product cited in: Cui, Gao, Me, Xu, Yu: "TSLP Protects Corneas From Pseudomonas aeruginosa Infection by Regulating Dendritic Cells and IL-23-IL-17 Pathway." in: Investigative ophthalmology & visual science, Vol. 59, Issue 10, pp. 4228-4237, 2018 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Mouse (Murine)).

Kummola, Ortutay, Chen, Caucheteux, Hämäläinen, Aittomäki, Yagi, Zhu, Pesu, Paul, Junttila: "IL-7Rα Expression Regulates Murine Dendritic Cell Sensitivity to Thymic Stromal Lymphopoietin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 10, pp. 3909-3918, 2017 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Mullighan, Collins-Underwood, Phillips, Loudin, Liu, Zhang, Ma, Coustan-Smith, Harvey, Willman, Mikhail, Meyer, Carroll, Williams, Cheng, Heerema, Basso, Pession, Pui, Raimondi, Hunger, Downing et al.: "Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. ..." in: Nature genetics, Vol. 41, Issue 11, pp. 1243-6, 2009 (PubMed). Method employed by authors: Western Blotting (WB), Western Blotting (WB), Western Blotting (WB) (Sample species: Mouse (Murine)).

Osborn, Ryan, Kirchhof, Panoskaltsis-Mortari, Mortari, Tudor: "Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis." in: Blood, Vol. 103, Issue 3, pp. 843-51, 2004 (PubMed). Method employed by authors: Neutralization (Neut), Neutralization (Neut), Neutralization (Neut) (Sample species: Mouse (Murine)).

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