CRLF2 antibody (Cytokine Receptor-Like Factor 2) (AA 25-231)

Details for Product anti-CRLF2 Antibody No. ABIN4899885
Antigen
  • CRLF2
  • CRL2
  • CRLF2Y
  • TSLPR
  • CRLM2
  • Ly114
  • Tpte2
  • Tslpr
  • Crl2
  • cytokine receptor like factor 2
  • cytokine receptor-like factor 2
  • CRLF2
  • Crlf2
Epitope
AA 25-231
5
5
4
4
2
2
2
2
2
1
1
1
1
Reactivity
Human
75
33
23
Host
Mouse
78
19
3
Clonality (Clone)
Monoclonal ()
Conjugate
This CRLF2 antibody is un-conjugated
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Western Blotting (WB)
55
30
26
15
15
6
5
2
2
1
Options
Immunogen Mouse myeloma cell line NS0-derived recombinant human TSLP R, Gly25-Lys231, Accession # Q9HC73
Clone 147036
Isotype IgG1
Specificity Detects human TSLP R in direct ELISAs and Western blots. Does not cross-react with recombinant mouse TSLP R.
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Plasmids, Primers & others Plasmids, Primers & others CRLF2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TSLP R (CRLF2 Antibody Abstract)
Background Alternative Names: CRL2, CRL2cytokine receptor CRL2 precusor, CRLF2, CRLF2Y, CRLM-2, Cytokine receptor-like 2, cytokine receptor-like factor 2, ILXR, IL-XR, P2RY8/CRLF2 fusion, PCOR1, Thymic stromal lymphopoietin protein receptor, thymic stromal lymphopoietin receptor, thymic stromal-derived lymphopoietin receptor, TSLP receptor, TSLPR
Gene ID 64109
UniProt Q9HC73
Application Notes Western Blot 1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) antibody (ABIN4899885) Detection of TSLP R in Human PBMC Monocytes by Flow Cytometry. Human PBMC monocytes w...
Product cited in: Takahashi, Sugaya, Suga, Oka, Kawaguchi, Miyagaki, Fujita, Sato: "Thymic Stromal Chemokine TSLP Acts through Th2 Cytokine Production to Induce Cutaneous T-cell Lymphoma." in: Cancer research, Vol. 76, Issue 21, pp. 6241-6252, 2016 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Kubo, Kamekura, Kumagai, Kawata, Yamashita, Mitsuhashi, Kojima, Sugimoto, Yoneta, Sumikawa, Yamashita, Sato, Himi, Ichimiya: "ΔNp63 controls a TLR3-mediated mechanism that abundantly provides thymic stromal lymphopoietin in atopic dermatitis." in: PLoS ONE, Vol. 9, Issue 8, pp. e105498, 2015 (PubMed). Method employed by authors: Immunocytochemistry (ICC), Immunocytochemistry (ICC) (Sample species: Human).

Shan, Redhu, Saleh, Halayko, Chakir, Gounni: "Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 12, pp. 7134-43, 2010 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Semlali, Jacques, Koussih, Gounni, Chakir: "Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-dependent pathway." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 4, pp. 844-50, 2010 (PubMed). Method employed by authors: Western Blotting (WB), Western Blotting (WB), Western Blotting (WB) (Sample species: Human).

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