Peroxiredoxin 1 antibody (AA 106-117)

Catalog No. ABIN490015

Product Details anti-Peroxiredoxin 1 Antibody

Target: Peroxiredoxin 1 (PRDX1)

Binding Specificity: AA 106-117

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig, Bat, Hamster, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human PRDX1 / Peroxiredoxin 1. Reported variants represent identical protein (NP_002565.1, NP_859047.1, NP_859048.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Rabbit, Pig (100%) Opossum (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-SDPKRTIAQDYG from an internal region of human PRDX1 / Peroxiredoxin 1 (NP_859048.1). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Rabbit, Pig (100%), Opossum (92%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (2.5 μg/mL), Peptide-ELISA (1:32000), WB (0.01 - 0.03 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx. 23 to 24kD band observed in lysates of cell lines HEK293, A431 and HepG2 (calculated MW of 22.1kD according to NP_859048.1). Recommended concentration: 0.01-0.03 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Alternative Name: PRDX1 / Peroxiredoxin 1 (PRDX1 Products)

Synonyms: MSP23 antibody, NKEF-A antibody, NKEFA antibody, PAG antibody, PAGA antibody, PAGB antibody, PRX1 antibody, PRXI antibody, TDPX2 antibody, NkefA antibody, OSF-3 antibody, OSF3 antibody, Paga antibody, PrdxI antibody, PrxI antibody, TDX2 antibody, TPxA antibody, Tdpx2 antibody, prx1 antibody, Hbp23 antibody, MGC80194 antibody, MGC84820 antibody, PRDX1 antibody, msp23 antibody, nkefa antibody, pag antibody, paga antibody, pagb antibody, prx-1 antibody, prxi antibody, tdpx2 antibody, hm:zehl0637 antibody, zgc:110343 antibody, TPX-2 antibody, peroxiredoxin 1 antibody, peroxiredoxin 1 S homeolog antibody, peroxiredoxin-1 pseudogene antibody, PRDX1 antibody, Prdx1 antibody, prdx1.S antibody, prdx1 antibody, LOC100350232 antibody

Background: Name/Gene ID: PRDX1

Synonyms: PRDX1, MSP23, PAGB, Peroxiredoxin-1, PRX1, NKEFA, Peroxiredoxin 1, Thioredoxin peroxidase 2, NKEF-A, PAG, PRXI, TDPX2

Gene ID: 5052

NCBI Accession: NP_859048

UniProt: Q06830

Pathways: p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events