FMR1 antibody (AA 116-130)

Catalog No. ABIN490019

Product Details anti-FMR1 Antibody

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Binding Specificity: AA 116-130

Reactivity: Human, Mouse, Rat, Dog, Monkey, Rabbit, Pig, Bat, Hamster

Host: Goat

Clonality: Polyclonal

Conjugate: This FMR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human FMR1.

No Cross-Reactivity: Chicken

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus (100%) Bovine (93%) Xenopus (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-NPNKPATKDTFHKIK from an internal region of human FMR1 (NP_002015.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus (100%), Bovine (93%), Xenopus (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (2.5 μg/mL), Peptide-ELISA (1:32000), WB (0.3 - 1 μg/mL)

Usage: Approx 70Da band observed in lysates of cell lines HeLa and Jurkat (calculated MW of 71.2  kDa according to NP_002015.1).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Alternative Name: FMR1 / FMRP (FMR1 Products)

Synonyms: AT24755 antibody, BcDNA:GM08679 antibody, CG6203 antibody, Dmel\\CG6203 antibody, EP(3)3517 antibody, FMR antibody, FMR1 antibody, FMRP antibody, FMRp antibody, FXR antibody, Fmrp antibody, cg6203 antibody, dFMR antibody, dFMR1 antibody, dFMRP antibody, dFXR antibody, dFXR1 antibody, dFXRP antibody, dFmr1 antibody, dFmrp antibody, dfmr antibody, dfmr1 antibody, dfxr antibody, dfxr1 antibody, dmfr1 antibody, fmr antibody, fmr1 antibody, FRAXA antibody, POF antibody, POF1 antibody, zFMR1 antibody, Fmr-1 antibody, CG6203 gene product from transcript CG6203-RC antibody, fragile X mental retardation 1 antibody, fragile X mental retardation syndrome 1 antibody, Fmr1 antibody, FMR1 antibody, fmr1 antibody

Background: Name/Gene ID: FMR1

Synonyms: FMR1, FMRP, POF, Protein FMR-1, Premature ovarian failure 1, Fragile X mental retardation 1, FRAXA, POF1

Gene ID: 2332

NCBI Accession: NP_002015

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development