TNFRSF10B antibody (Tumor Necrosis Factor Receptor Superfamily, Member 10b) (AA 53-177)

Details for Product anti-TNFRSF10B Antibody No. ABIN4900408, Supplier: Log in to see
Antigen
  • TNFRSF10B
  • dr5
  • cd262
  • killer
  • trick2
  • trickb
  • xDR-M1
  • xDR-M2
  • ztnfr9
  • trailr2
  • trick2a
  • trick2b
  • CD262
  • DR5
  • KILLER
  • KILLER/DR5
  • TRAIL-R2
  • TRAILR2
  • TRICK2
  • TRICK2A
  • TRICK2B
  • TRICKB
  • ZTNFR9
  • Ly98
  • MK
  • tumor necrosis factor receptor superfamily, member 10b
  • tumor necrosis factor receptor superfamily member 10b S homeolog
  • tumor necrosis factor receptor superfamily member 10b L homeolog
  • tumor necrosis factor receptor superfamily member 10b
  • TNF receptor superfamily member 10b
  • Tnfrsf10b
  • TNFRSF10B
  • tnfrsf10b.S
  • tnfrsf10b.L
  • tnfrsf10b
Alternatives
anti-Human TNFRSF10B antibody for Flow Cytometry
Epitope
AA 53-177
49
14
13
12
11
10
10
9
8
8
8
5
5
5
5
5
4
4
4
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
326
70
29
2
1
1
1
1
Host
Goat
184
170
7
6
2
2
Clonality
Polyclonal
Conjugate
This TNFRSF10B antibody is un-conjugated
21
20
17
7
5
5
5
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
200
153
68
63
38
35
30
27
15
14
13
8
3
3
3
2
1
Options
Supplier
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Supplier Product No.
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Immunogen Mouse myeloma cell line NS0-derived recombinant mouse TRAIL R2/TNFRSF10B, Asn53-Ser177, Accession # Q6GSD9
Isotype IgG
Specificity Detects mouse TRAIL R2 in direct ELISAs and Western blots. In direct ELISAs, less than 5 % cross-reactivity with recombinant human (rh) TRAIL R2 is observed.
Purification Antigen Affinity-purified
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Plasmids, Primers & others Plasmids, Primers & others TNFRSF10B products on genomics-online (e.g. as negative or positive controls)
Antigen Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B)
Alternative Name TRAIL R2/TNFRSF10B (TNFRSF10B Antibody Abstract)
Background Alternative Names: CD262, CD262 antigen, death domain containing receptor for TRAIL/Apo-2L, Death receptor 5, DR5, DR5TRICK2B, Fas-like protein, KILLER/DR5, KILLERapoptosis inducing protein TRICK2A/2B, TNF-related apoptosis-inducing ligand receptor 2, TNFRSF10B, TRAIL receptor 2, TRAILR2, TRAIL-R2apoptosis inducing receptor TRAIL-R2, TRAILR2cytotoxic TRAIL receptor-2, TRICK2, TRICK2A, TRICKB, tumor necrosis factor receptor superfamily member 10B, tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9, ZTNFR9
Gene ID 8795
UniProt Q6GSD9
Pathways p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
Application Notes Western Blot 0.1 μg/mL
Flow Cytometry 0.25 μg/10^6 cells
Neutralization 0.4-1.2 μg/mL
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Neutralization (Neut) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 53-177) antibody (ABIN4900408) Cytotoxicity Induced by TRAIL/TNFSF10 and Neutralization by Mouse TRAIL R2/TNFRSF10B ...
Product cited in: Shekhar, Miles, Gupte, Taylor, Tascone, Walkley, Hawkins: "IAP antagonists sensitize murine osteosarcoma cells to killing by TNFα." in: Oncotarget, Vol. 7, Issue 23, pp. 33866-86, 2016 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Lundqvist, Yokoyama, Smith, Berg, Childs: "Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells." in: Blood, Vol. 113, Issue 24, pp. 6120-7, 2009 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Mouse (Murine)).

Park, Wu, Choi, Najafi, Emami, Safa: "P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5." in: Biochemical pharmacology, Vol. 72, Issue 3, pp. 293-307, 2006 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

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