CSF1R antibody (Colony Stimulating Factor 1 Receptor) (AA 20-512)

Details for Product anti-CSF1R Antibody No. ABIN4900601, Supplier: Log in to see
Antigen
  • AI323359
  • CD115
  • CSF-1R
  • Csfmr
  • Fim-2
  • Fms
  • M-CSF-R
  • M-CSFR
  • C-FMS
  • CSFR
  • FIM2
  • FMS
  • HDLS
  • PDGFRB
  • MGC89146
  • CSF-1-R
  • c-fms
  • mrfms
  • CSF1
  • M-CSF
  • csf1r
  • fms
  • panther
  • colony stimulating factor 1 receptor
  • macrophage colony-stimulating factor receptor
  • colony stimulating factor 1 receptor, a
  • Csf1r
  • CSF1R
  • m-csfr
  • csf1r
  • csf1ra
Alternatives
anti-Human CSF1R antibody for Immunocytochemistry
Epitope
AA 20-512, Pro54Ala-Mutant
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Reactivity
Human
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230
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Host
Mouse
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Clonality (Clone)
Monoclonal ()
Conjugate
This CSF1R antibody is un-conjugated
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Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS)
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Options
Supplier
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Supplier Product No.
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Immunogen Mouse myeloma cell line NS0-derived recombinant human M-CSF R/CD115, Ile20-Glu512 (Pro54Ala), Accession # P07333.2
Clone 61708
Isotype IgG1
Specificity Detects human M-CSF R/CD115 in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) GM-CSF R alpha or rhGM-CSF R beta .
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Alternative Name M-CSF R/CD115 (CSF1R Antibody Abstract)
Background Alternative Names: CD115, CD115 antigen, C-FMS, colony stimulating factor 1 receptor, CSF1R, CSF-1-R, CSFR, EC 2.7.10.1, FMS proto-oncogene, FMSFIM2, macrophage colony stimulating factor I receptor, macrophage colony-stimulating factor 1 receptor, McDonough feline sarcoma viral (v-fms) oncogene homolog, MCSFR, M-CSFR, Proto-oncogene c-Fms
Gene ID 1436
UniProt P07333
Pathways RTK Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
Application Notes Flow Cytometry 0.25 μg/10^6 cells
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Product cited in: Bellora, Dondero, Corrias, Casu, Regis, Caliendo, Moretta, Cazzola, Elena, Vinti, Locatelli, Bottino, Castriconi: "Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 199, Issue 4, pp. 1516-1525, 2017 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Lee, Kim, Jun, Yoo, Woo, Choi, Lee, Song, Sohn, Park-Min, Ivashkiv, Ji: "Direct inhibition of human RANK+ osteoclast precursors identifies a homeostatic function of IL-1beta." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 10, pp. 5926-34, 2010 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Riccioni, Senese, Diverio, Riti, Mariani, Boe, LoCoco, Foà, Peschle, Sporn, Testa: "Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels." in: Leukemia research, Vol. 32, Issue 8, pp. 1244-58, 2008 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Riccioni, Diverio, Mariani, Buffolino, Riti, Saulle, Petrucci, Cedrone, Lo-Coco, Foà, Peschle, Testa: "Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts." in: Stem cells (Dayton, Ohio), Vol. 25, Issue 8, pp. 1862-71, 2007 (PubMed). Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

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