Integrin alpha 4 (ITGA4) antibody

Details for Product No. ABIN4900793, Supplier: Log in to see
Antigen
  • CD49D
  • IA4
  • LOC100219853
  • integrin subunit alpha 4
  • integrin alpha 4
  • integrin subunit alpha 4 S homeolog
  • ITGA4
  • Itga4
  • itga4.S
Alternatives
anti-Human Integrin alpha 4 antibody for Indirect Immunofluorescence Assay
Reactivity
Human
355
266
101
20
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Host
Mouse
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141
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1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
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63
35
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Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
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23
13
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4
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Options
Supplier
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Supplier Product No.
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Immunogen DX-3 human melanoma cell line
Clone 7-2R
Isotype IgG1
Specificity Detects human Integrin alpha 4/CD49d. Recognizes the human Integrin alpha 4/CD49d subunit.
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Antigen
Alternative Name ITGA4 (ITGA4 Antibody Abstract)
Background Alternative Names: 269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), ITGA4, MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4, VLA-4 subunit alpha
Gene ID 3676
Pathways Integrin Complex
Application Notes Flow Cytometry 0.25 μg/10^6 cells
Immunocytochemistry 8-25 μg/mL
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-Integrin alpha 4 (ITGA4) antibody (ABIN4900793) Detection of Integrin alpha 4/CD49d in Human Blood Lymphocytes by Flow Cytometry. Hum...
Immunocytochemistry (ICC) image for anti-Integrin alpha 4 (ITGA4) antibody (ABIN4900793) Integrin alpha 4/CD49d in U937 Human Cell Line. Integrin alpha 4/ CD49d was detected ...
Product cited in: Zhang, Fu, Hu, Dong, Song, Song: "C6-ceramide nanoliposome suppresses tumor metastasis by eliciting PI3K and PKCζ tumor-suppressive activities and regulating integrin affinity modulation." in: Scientific reports, Vol. 5, pp. 9275, 2015 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

van Grevenstein, Hofland, van Rossen, van Koetsveld, Jeekel, van Eijck: "Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers." in: Digestive diseases and sciences, Vol. 52, Issue 10, pp. 2775-83, 2007 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Silverman, Haas, Rad, Arbab, Koch: "The role of vascular cell adhesion molecule 1/ very late activation antigen 4 in endothelial progenitor cell recruitment to rheumatoid arthritis synovium." in: Arthritis and rheumatism, Vol. 56, Issue 6, pp. 1817-26, 2007 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Carman, Springer: "A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them." in: The Journal of cell biology, Vol. 167, Issue 2, pp. 377-88, 2004 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

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