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FCAR antibody

FCAR Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4903651
  • Target See all FCAR Antibodies
    FCAR (Fc Fragment of IgA, Receptor For (FCAR))
    Reactivity
    • 62
    • 21
    • 9
    • 5
    • 3
    Human
    Host
    • 49
    • 18
    Rabbit
    Clonality
    • 50
    • 16
    • 1
    Polyclonal
    Conjugate
    • 28
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCAR antibody is un-conjugated
    Application
    • 27
    • 24
    • 19
    • 13
    • 13
    • 9
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    A synthetic Peptide of human FCAR
    Isotype
    IgG
    Top Product
    Discover our top product FCAR Primary Antibody
  • Application Notes
    WB 1:200 - 1:1000
    Comment

    Isoform A,1, isoform A,2 and isoform A,3 are differentially expressed between blood and mucosal myeloid cells, Isoform A,1, isoform A,2 and isoform A,3 are expressed in monocytes, Isoform A,1 and isoform A,2 are expressed in alveolar macrophages

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    FCAR (Fc Fragment of IgA, Receptor For (FCAR))
    Alternative Name
    FCAR (FCAR Products)
    Synonyms
    CD89 antibody, Fc fragment of IgA receptor antibody, Fc fragment of IgA, receptor for antibody, FCAR antibody
    Background
    This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Molecular Weight
    32.265 kDa
    Gene ID
    2204
    UniProt
    P24071
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