FCAR antibody
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- Target See all FCAR Antibodies
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FCAR antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- A synthetic Peptide of human FCAR
- Isotype
- IgG
- Top Product
- Discover our top product FCAR Primary Antibody
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- Application Notes
- WB 1:200 - 1:1000
- Comment
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Isoform A,1, isoform A,2 and isoform A,3 are differentially expressed between blood and mucosal myeloid cells, Isoform A,1, isoform A,2 and isoform A,3 are expressed in monocytes, Isoform A,1 and isoform A,2 are expressed in alveolar macrophages
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
- Alternative Name
- FCAR (FCAR Products)
- Synonyms
- CD89 antibody, Fc fragment of IgA receptor antibody, Fc fragment of IgA, receptor for antibody, FCAR antibody
- Background
- This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Molecular Weight
- 32.265 kDa
- Gene ID
- 2204
- UniProt
- P24071
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