INHBB antibody

Catalog No. ABIN4904063

Product Details anti-INHBB Antibody

Target: INHBB (Inhibin, beta B (INHBB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INHBB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Purification: Affinity purification

Immunogen: Recombinant protein of human INHBB.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 , IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for INHBB

Target: INHBB (Inhibin, beta B (INHBB))

Alternative Name: INHBB (INHBB Products)

Synonyms: actbb antibody, actbetaB antibody, inhibin antibody, inhibin, beta B antibody, inhibin beta B L homeolog antibody, inhibin beta B subunit antibody, inhibin beta B antibody, inhibin beta-B antibody, inhibin beta B chain antibody, inhbb antibody, inhbb.L antibody, INHBB antibody, Inhbb antibody, LOC100719829 antibody

Gene ID: 3625

UniProt: P09529

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion