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MAPK8IP1 antibody

MAPK8IP1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4904305
  • Target See all MAPK8IP1 Antibodies
    MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
    Reactivity
    • 50
    • 30
    • 17
    Human, Mouse
    Host
    • 49
    • 1
    • 1
    Rabbit
    Clonality
    • 51
    Polyclonal
    Conjugate
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPK8IP1 antibody is un-conjugated
    Application
    • 44
    • 24
    • 13
    • 13
    • 9
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human MAPK8IP1.
    Isotype
    IgG
    Top Product
    Discover our top product MAPK8IP1 Primary Antibody
  • Application Notes
    WB 1:200-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C.
  • Target
    MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
    Alternative Name
    MAPK8IP1 (MAPK8IP1 Products)
    Synonyms
    IB1 antibody, JIP-1 antibody, Jip1 antibody, Prkm8ip antibody, Skip antibody, mjip-2a antibody, JIP1 antibody, Jip-1 antibody, Mapk8ip antibody, PRKM8IP antibody, mitogen-activated protein kinase 8 interacting protein 1 antibody, MAPK8IP1 antibody, Mapk8ip1 antibody
    Gene ID
    9479
    UniProt
    Q9UQF2
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