MMP20 antibody

Catalog No. ABIN4904396

Product Details anti-MMP20 Antibody

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP20 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: A synthetic peptide of human MMP20

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:1000
IHC 1:20 - 1:50

Comment:

Expressed specifically in the enamel organ

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for MMP20

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Alternative Name: MMP20 (MMP20 Products)

Synonyms: AI2A2 antibody, MMP-20 antibody, MMP25 antibody, MMP20 antibody, mmp20 antibody, matrix metallopeptidase 20 antibody, matrix metallopeptidase 20 L homeolog antibody, matrix metallopeptidase 20 (enamelysin) antibody, MMP20 antibody, mmp20.L antibody, Mmp20 antibody

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.

Molecular Weight: 54.387 kDa

Gene ID: 9313

UniProt: O60882