NFYA antibody

Catalog No. ABIN4904531

Product Details anti-NFYA Antibody

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFYA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Purification: Affinity purification

Immunogen: Recombinant protein of human NFYA.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000 , IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for NFYA

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Alternative Name: NFYA (NFYA Products)

Synonyms: wu:fb16e03 antibody, ik:tdsubc_2b6 antibody, xx:tdsubc_2b6 antibody, NFYA antibody, CBF-A antibody, CBF-B antibody, HAP2 antibody, NF-YA antibody, AA407810 antibody, Cbf-b antibody, SEZ-10 antibody, SEZ10 antibody, nuclear transcription factor Y, alpha antibody, nuclear transcription factor Y subunit alpha antibody, nuclear transcription factor-Y alpha antibody, nfya antibody, NFYA antibody, Nfya antibody

Gene ID: 4800

UniProt: P23511

Pathways: Regulation of Lipid Metabolism by PPARalpha