PCDHa13 antibody

Catalog No. ABIN4904701

Product Details anti-PCDHa13 Antibody

Target: PCDHa13 (Protocadherin alpha 13 (PCDHa13))

Reactivity: Mouse, Rat, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHa13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Purification: Affinity purification

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for PCDHa13

Target: PCDHa13 (Protocadherin alpha 13 (PCDHa13))

Alternative Name: PCDHA13 (PCDHa13 Products)

Synonyms: CNR5 antibody, CNRN5 antibody, CNRS5 antibody, CRNR5 antibody, PCDH-ALPHA13 antibody, Cnr5 antibody, MGC165970 antibody, protocadherin alpha 13 antibody, PCDHA13 antibody, Pcdha13 antibody

Gene ID: 56136

UniProt: Q9Y5I0