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PKN1 antibody
PKN1
Reactivity: Human, Mouse, Rat
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PKN1 Antibody
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Target
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PKN1
(Protein Kinase N1 (PKN1))
Reactivity
All reactivities for PKN1 antibodies
Human, Mouse, Rat
Host
All hosts for PKN1 antibodies
Rabbit
Clonality
All clonalities for PKN1 antibodies
Polyclonal
Conjugate
All conjugates for PKN1 antibodies
This PKN1 antibody is un-conjugated
Application
All applications for PKN1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Characteristics
The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification
Affinity purification
Immunogen
Recombinant protein of human PKN1.
Isotype
IgG
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Discover our top product PKN1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:500-1:1000 , IHC 1:50-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles.
Storage
-20 °C
Storage Comment
Store at -20°C.
Target Details for PKN1
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Target
PKN1
(Protein Kinase N1 (PKN1))
Alternative Name
PKN1 (PKN1 Products )
Synonyms
DBK antibody, PAK-1 antibody, PAK1 antibody, PKN antibody, PKN-ALPHA antibody, PRK1 antibody, PRKCL1 antibody, F730027O18Rik antibody, Pkn antibody, Prkcl1 antibody, Stk3 antibody, PKN1 antibody, 3-2 antibody, CG2049 antibody, CG2055 antibody, CT6637 antibody, CT6660 antibody, DPKN antibody, Dmel\\CG2049 antibody, Dpkn antibody, PRK2 antibody, Pk45C antibody, Pk?3 antibody, dPKN antibody, l(2)06736 antibody, l(2)45Ca antibody, v(2)rG232 antibody, protein kinase N1 antibody, protein kinase N1b antibody, Protein kinase N antibody, PKN1 antibody, Pkn1 antibody, pkn1b antibody, pkn1 antibody, Pkn antibody
Gene ID
5585
UniProt
Q9UN73
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