UQCRB antibody

Catalog No. ABIN4905562

Product Details anti-UQCRB Antibody

Target: UQCRB (Ubiquinol-Cytochrome C Reductase Binding Protein (UQCRB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UQCRB antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: UQCRB (ubiquinol-cytochrome c reductase binding protein), also known as complex III subunit VII, ubiquinol-cytochrome c reductase complex 14 kDa protein and QCR7, is a 111 amino acid mitochondrion inner membrane protein. UQCRB is a component of the ubiquinol-cytochrome c reductase complex, also known as complex III or cytochrome b-c1 complex, which is a constituent of the mitochondrial respiratory chain. The ubiquinol-cytochrome c reductase complex is composed of two core proteins (UQCRC1 and UQCRC2), three respiratory subunits (cytochrome c1, cytochrome b and Rieske) and six low-molecular weight proteins (UQCRH, UQCRB, QP-C, UQCR10, UQCR11 and a cleavage product of Rieske). UQCRB binds ubiquinone and is involved in the transfer of electrons across the mitochondrion inner membrane. Mutations in the gene that encodes UQCRB have been linked to mitochondrial complex III deficiency (CIII deficiency), a condition characterized by congenital lactic acidosis.

Purification: Affinity purification

Immunogen: Recombinant protein of human UQCRB.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for UQCRB

Target: UQCRB (Ubiquinol-Cytochrome C Reductase Binding Protein (UQCRB))

Alternative Name: UQCRB (UQCRB Products)

Synonyms: MC3DN3 antibody, QCR7 antibody, QP-C antibody, QPC antibody, UQBC antibody, UQBP antibody, UQCR6 antibody, UQPC antibody, 2210415M14Rik antibody, Uqcrbl antibody, im:6900881 antibody, zgc:109893 antibody, cr14 antibody, ubiquinol-cytochrome c reductase binding protein antibody, cytochrome b-c1 complex subunit 7 antibody, putative ubiquinol-cytochrome c reductase complex 14 kDa protein antibody, cytochrome b-c1 complex subunit 7-like antibody, UQCRB antibody, Uqcrb antibody, uqcrb antibody, LOC701223 antibody, LOC705124 antibody, Smp_024120 antibody, LOC102598697 antibody

Gene ID: 7381

UniProt: P14927