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WRNIP1 antibody

WRNIP1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4905632
  • Target See all WRNIP1 Antibodies
    WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
    Reactivity
    • 26
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 25
    • 1
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This WRNIP1 antibody is un-conjugated
    Application
    • 24
    • 16
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene.
    Purification
    Affinity purification
    Immunogen
    Recombinant protein of human WRNIP1.
    Isotype
    IgG
    Top Product
    Discover our top product WRNIP1 Primary Antibody
  • Application Notes
    WB 1:1000-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C.
  • Target
    WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
    Alternative Name
    WRNIP1 (WRNIP1 Products)
    Synonyms
    WRNIP1 antibody, wrnip1 antibody, RP11-420G6.2 antibody, WHIP antibody, bA420G6.2 antibody, zgc:85976 antibody, 4833444L21Rik antibody, Wrnip antibody, Whip antibody, Werner helicase interacting protein 1 antibody, Werner helicase interacting protein 1 L homeolog antibody, ATPase WRNIP1 antibody, WRNIP1 antibody, wrnip1.L antibody, wrnip1 antibody, EDI_075920 antibody, CpipJ_CPIJ017857 antibody, PITG_07216 antibody, VDBG_02914 antibody, Wrnip1 antibody, PGTG_08805 antibody
    Gene ID
    56897
    UniProt
    Q96S55
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