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CBX8 antibody

CBX8 Reactivity: Human WB Host: Mouse Monoclonal 12C7 unconjugated
Catalog No. ABIN4907491
  • Target See all CBX8 Antibodies
    CBX8 (Chromobox Homolog 8 (CBX8))
    Reactivity
    • 63
    • 44
    • 18
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 61
    • 9
    • 1
    Mouse
    Clonality
    • 63
    • 8
    Monoclonal
    Conjugate
    • 37
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CBX8 antibody is un-conjugated
    Application
    • 56
    • 32
    • 18
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Purification
    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This CBX8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the C-terminal region of human CBX8.
    Clone
    12C7
    Isotype
    IgG1
    Top Product
    Discover our top product CBX8 Primary Antibody
  • Application Notes
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    CBX8 (Chromobox Homolog 8 (CBX8))
    Alternative Name
    CBX8 (CBX8 Products)
    Synonyms
    cbx8 antibody, MGC147589 antibody, Pc3 antibody, PC3 antibody, RC1 antibody, chromobox 8 antibody, chromobox 8 S homeolog antibody, chromobox homolog 8a (Pc class homolog, Drosophila) antibody, cbx8 antibody, CBX8 antibody, Cbx8 antibody, cbx8.S antibody, cbx8a antibody
    Background

    Synonyms: PC3, RC1, Chromobox protein homolog 8, Polycomb 3 homolog, hPc3, Rectachrome 1, CBX8

    Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

    Gene ID
    57332
    UniProt
    Q9HC52
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