Lamin B1 antibody (Internal Region)

Catalog No. ABIN4916693

Product Details anti-Lamin B1 Antibody

Target: Lamin B1 (LMNB1)

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: Reacts with human 66k Da Lamin-B1

Purification: Purified (protein A)

Immunogen: Synthetic peptide derived from internal domain of human Lamin-B1.

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only :
- WB : 1/500 to 1/2000 - IHC : 1/100 to 1/1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for Lamin B1

Target: Lamin B1 (LMNB1)

Alternative Name: Lamin-B1 (LMNB1 Products)

Synonyms: MGC52550 antibody, Lamin-L(I) antibody, lamin-b antibody, lmn antibody, lmn2 antibody, lmnb antibody, LMNB1 antibody, ADLD antibody, LMN antibody, LMN2 antibody, LMNB antibody, fc06g01 antibody, wu:fc06g01 antibody, lamin B1 L homeolog antibody, lamin B1 antibody, lmnb1.L antibody, lmnb1 antibody, LMNB1 antibody, Lmnb1 antibody

Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Defects in LMNB1 are the cause of leukodystrophy demyelinating autosomal dominant adult-onset (ADLD)

UniProt: P20700

Pathways: Apoptosis, Caspase Cascade in Apoptosis