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CYP1A2 antibody (AA 185-320)

CYP1A2 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4950724
  • Target See all CYP1A2 Antibodies
    CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))
    Binding Specificity
    • 16
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 185-320
    Reactivity
    Human, Mouse, Rat
    Host
    • 52
    • 13
    • 2
    Rabbit
    Clonality
    • 55
    • 12
    Polyclonal
    Conjugate
    • 36
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP1A2 antibody is un-conjugated
    Application
    • 57
    • 33
    • 23
    • 18
    • 17
    • 13
    • 13
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogen
    Amino acids 185-320 of human CYP1A2 were used as the immunogen for the CYP1A2 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product CYP1A2 Primary Antibody
  • Application Notes
    Optimal dilution of the CYP1A2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the CYP1A2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))
    Alternative Name
    CYP1A2 (CYP1A2 Products)
    Synonyms
    CP12 antibody, P3-450 antibody, P450(PA) antibody, CYP1A2 antibody, CYPIA2 antibody, P450-PM4 antibody, Cyp1a1 antibody, P450-3 antibody, CYPD45 antibody, P-450d antibody, RATCYPD45 antibody, CYP1A5 antibody, CP450 antibody, CYP-IA2 antibody, cytochrome P450 family 1 subfamily A member 2 antibody, cytochrome P450 1A2 antibody, cytochrome P450 LM4 antibody, cytochrome P450, family 1, subfamily A, polypeptide 2 antibody, cytochrome P450, family 1, subfamily a, polypeptide 2 antibody, cytochrome P450 1A2-like antibody, CYP1A2 antibody, LOC100328937 antibody, Cyp1a2 antibody, VDBG_06455 antibody, LOC101825565 antibody, LOC102130662 antibody
    Background
    CYP1A2 (Cytochrome P450, Subfamily I, Polypeptide 2) is a member of the cytochrome P450 mixed-function oxidase system and is involved in the metabolism of xenobiotics in the body. CYP1A2 is a member of the cytochrome P450 superfamily of enzymes. In humans, the CYP1A2 enzyme is encoded by the CYP1A2 gene. CYP1A2 localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The CYP1A2 gene encodes a P450 enzyme involved in O-deethylation of phenacetin. Ikeya et al. (1989) found that the human CYP1A2 gene spans almost 7.8 kb and contains 7 exons. The CYP1A2 gene is mapped on 15q24.1. CYP1A2 accounts for nearly 15 % of the cytochrome P450 in the human liver. CYP1A2 displays higher activity in men than in women, and is inhibited by oral contraceptives. Inducers of CYP1A2 include cruciferous vegetables. Cigarette smoking has also been shown to increase CYP1A2 activity. Expression of CYP1A2 appears to be induced by various dietary constituents.
    UniProt
    P05177
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