Monoamine Oxidase A antibody

Catalog No. ABIN4951664

Product Details anti-Monoamine Oxidase A Antibody

Target: Monoamine Oxidase A (MAOA)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Monoamine Oxidase A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Amino acids REVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWER of human MAOA were used as the immunogen for the MAOA antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MAOA antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the MAOA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Monoamine Oxidase A

Target: Monoamine Oxidase A (MAOA)

Alternative Name: Monoamine Oxidase A / MAOA (MAOA Products)

Synonyms: MAO-A antibody, 1110061B18Rik antibody, AA407771 antibody, Mao antibody, MAOA antibody, LOC100221249 antibody, Z-MAO antibody, maob antibody, moa antibody, wu:fb68b05 antibody, wu:fo76d11 antibody, wu:fq38g06 antibody, zgc:85761 antibody, monoamine oxidase A antibody, monoamine oxidase A L homeolog antibody, amine oxidase [flavin-containing] A antibody, monoamine oxidase antibody, MAOA antibody, Maoa antibody, maoa.L antibody, mll3668 antibody, maoa antibody, LOC100221249 antibody, mao antibody

Background: Monoamine oxidase A is an enzyme that in humans is encoded by the MAO-A gene. MAOA is an isozyme of monoamine oxidase which is also mapped on Xp11.3. MAOA degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Mutation in MAOA results in monoamine oxidase deficiency, or Brunner syndrome. In humans, there is a 30-base repeat sequence repeated in one of several different numbers of times in the promoter region of the gene coding for MAOA. MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34 % in patients with major depressive disorder. Inhibition of MAOA prevented apoptosis, and serum starvation of cortical brain cells from Maoa-deficient mice resulted in reduced apoptosis compared with wildtype mice.

UniProt: P21397