Monoamine Oxidase B antibody

Catalog No. ABIN4951665

Product Details anti-Monoamine Oxidase B Antibody

Target: Monoamine Oxidase B (MAOB)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Monoamine Oxidase B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Amino acids REILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLER of human MAOB were used as the immunogen for the MAOB antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MAOB antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the MAOB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Monoamine Oxidase B

Target: Monoamine Oxidase B (MAOB)

Alternative Name: Monoamine Oxidase B / MAOB (MAOB Products)

Synonyms: MAOB antibody, Z-MAO antibody, maob antibody, moa antibody, wu:fb68b05 antibody, wu:fo76d11 antibody, wu:fq38g06 antibody, zgc:85761 antibody, MAOA antibody, 6330414K01Rik antibody, MAO-B antibody, monoamine oxidase B antibody, amine oxidase [flavin-containing] B antibody, monoamine oxidase antibody, monoamine oxidase B L homeolog antibody, MAOB antibody, Gbro_4276 antibody, LOC100223232 antibody, mao antibody, Maob antibody, maob.L antibody

Background: Monoamine oxidase B, also called MAO, BRAIN, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.

UniProt: P27338