PCSK2 antibody (AA 318-346)

Catalog No. ABIN3032333

Product Details anti-PCSK2 Antibody

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Binding Specificity: AA 318-346

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine, Pig

Purification: Purified

Immunogen: A portion of amino acids 318-346 from the human protein was used as the immunogen for this PCSK2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the PCSK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C for up to one month. For long term, aliquot the PCSK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for PCSK2

Target: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Alternative Name: PCSK2 (PCSK2 Products)

Synonyms: NEC 2 antibody, NEC-2 antibody, NEC2 antibody, PC2 antibody, SPC2 antibody, PCSK2 antibody, 6330411F23Rik antibody, AI839700 antibody, Nec-2 antibody, Nec2 antibody, Phpp-2 antibody, pc2 antibody, nec2 antibody, spc2 antibody, pcsk2 antibody, pcsk2-A antibody, proprotein convertase subtilisin/kexin type 2 antibody, proprotein convertase subtilisin/kexin type 2 L homeolog antibody, PCSK2 antibody, pcsk2 antibody, Pcsk2 antibody, pcsk2.L antibody

Background: PCSK2 is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Its responsible for the release of glucagon from proglucagon in pancreatic A cells. [UniProt]

UniProt: P16519

Pathways: Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity