ELAVL1
Reactivity: Human
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Titration of the HuR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS pH 7.4 with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the HuR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
ELAV1 antibody, HUR antibody, Hua antibody, MelG antibody, HuR antibody, 2410055N02Rik antibody, W91709 antibody, elra antibody, fa25f08 antibody, fb59a02 antibody, fc60g02 antibody, hua antibody, wu:fa25f08 antibody, wu:fb59a02 antibody, wu:fc60g02 antibody, zHuA antibody, Elavl1 antibody, Xel-1 antibody, elav1 antibody, elrA antibody, hur antibody, melg antibody, p36 antibody, ElrA antibody, elavl1 antibody, elavl1-a antibody, elavl1-b antibody, ELAV like RNA binding protein 1 antibody, ELAV-like protein 1 antibody, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) antibody, ELAV like RNA binding protein 1a antibody, ELAV like RNA binding protein 1 L homeolog antibody, ELAV like RNA binding protein 1 S homeolog antibody, ELAVL1 antibody, Elavl1 antibody, elav1 antibody, elavl1a antibody, elavl1.L antibody, elavl1.S antibody
Background
ELAVL1/HuR is involved in 3'-UTR ARE-mediated MYC stabilization. It binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.