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IKBKG antibody
IKBKG
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
55AT986-5-78
unconjugated
Product Details anti-IKBKG Antibody
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Target
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IKBKG
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
Reactivity
All reactivities for IKBKG antibodies
Human
Host
All hosts for IKBKG antibodies
Mouse
Clonality
All clonalities for IKBKG antibodies
Monoclonal
Conjugate
All conjugates for IKBKG antibodies
This IKBKG antibody is un-conjugated
Application
All applications for IKBKG antibodies
Western Blotting (WB), ELISA
Purification
Purified
Immunogen
This IKK gamma antibody was raised using purified His-tagged recombinant full length human IKKg.
Clone
55AT986-5-78
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Titration of the IKK gamma antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:500
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the IKK gamma antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target Details for IKBKG
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Target
IKBKG
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
Alternative Name
IKK gamma (IKBKG Products )
Synonyms
AMCBX1 antibody, FIP-3 antibody, FIP3 antibody, Fip3p antibody, IKK-gamma antibody, IP antibody, IP1 antibody, IP2 antibody, IPD2 antibody, NEMO antibody, ZC2HC9 antibody, 1110037D23Rik antibody, AI848108 antibody, AI851264 antibody, AW124339 antibody, IKK[g] antibody, Nemo antibody, nemo antibody, fj33c07 antibody, wu:fj33c07 antibody, zgc:113492 antibody, MGC97885 antibody, IKBKG antibody, IKBKG_1 antibody, IKBKG_2 antibody, CG16910 antibody, DmIKK-gamma antibody, DmIKKgamma antibody, Dmel\\CG16910 antibody, Dmikkgamma antibody, IKK antibody, IKK[[gamma]] antibody, IKKg antibody, IKKgamma antibody, KEY antibody, Kenny antibody, Key antibody, dIKK antibody, dIKK-gamma antibody, dmIKKgamma antibody, inhibitor of nuclear factor kappa B kinase subunit gamma antibody, inhibitor of kappaB kinase gamma antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma antibody, inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog antibody, kenny antibody, IKBKG antibody, Ikbkg antibody, ikbkg antibody, ikbkg.L antibody, IKBKG_1 antibody, key antibody
Background
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
UniProt
Q9Y6K9
Pathways
NF-kappaB Signaling , RTK Signaling , TCR Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , M Phase , Production of Molecular Mediator of Immune Response , Hepatitis C , Protein targeting to Nucleus , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteins
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