Notch1 antibody (C-Term)

Catalog No. ABIN3028882

This Rabbit Polyclonal antibody specifically detects Notch1 in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for Notch1 antibody (C-Term) (ABIN3028882)

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Notch1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Notch1 Antibody

Binding Specificity: C-Term

Purification: Antigen affinity purified

Immunogen: This Notch1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 2403-2437 amino acids from the C-terminal region of mouse Notch1.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Notch1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Notch1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Notch1

Target: Notch1 (NOTCH1) (Notch 1 (NOTCH1))

Alternative Name: Notch1

Background: Notch1 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. It is involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. [UniProt]

UniProt: Q01705

Pathways: Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development