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TIGIT antibody (AA 12-142)

TIGIT Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4955607
  • Target See all TIGIT Antibodies
    TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
    Binding Specificity
    • 11
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 12-142
    Reactivity
    • 24
    • 11
    • 1
    Human, Mouse
    Host
    • 19
    • 14
    • 1
    • 1
    Rabbit
    Clonality
    • 18
    • 15
    • 2
    Polyclonal
    Conjugate
    • 23
    • 4
    • 4
    • 2
    • 1
    • 1
    This TIGIT antibody is un-conjugated
    Application
    • 16
    • 15
    • 14
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogen
    A portion of amino acids 12-142 from the human protein was used as the immunogen for this TIGIT antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TIGIT Primary Antibody
  • Application Notes
    Titration of the TIGIT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000
    Restrictions
    For Research Use only
  • Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the TIGIT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
    Alternative Name
    TIGIT (TIGIT Products)
    Synonyms
    VSIG9 antibody, VSTM3 antibody, WUCAM antibody, ENSMUSG00000071552 antibody, Vstm3 antibody, RGD1563191 antibody, T-cell immunoreceptor with Ig and ITIM domains antibody, T cell immunoreceptor with Ig and ITIM domains antibody, TIGIT antibody, Tigit antibody
    Background
    TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
    UniProt
    Q495A1
    Pathways
    Cancer Immune Checkpoints
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