TRPM7 antibody (AA 1821-1850)

Catalog No. ABIN3029239

Product Details anti-TRPM7 Antibody

Target: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Binding Specificity: AA 1821-1850

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPM7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Purified

Immunogen: A portion of amino acids 1821-1850 from the human protein was used as the immunogen for this TRPM7 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the TRPM7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TRPM7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for TRPM7

Target: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Alternative Name: TRPM7 (TRPM7 Products)

Synonyms: cb495 antibody, TRPM7 antibody, chak antibody, chak1 antibody, ltrpc7 antibody, trp-plik antibody, ALSPDC antibody, CHAK antibody, CHAK1 antibody, LTRPC7 antibody, TRP-PLIK antibody, 2310022G15Rik antibody, 4833414K03Rik antibody, 5033407O22Rik antibody, LTrpC-7 antibody, Ltpr7 antibody, Ltrpc7 antibody, TRPPLIK antibody, Chak antibody, Trp-plik antibody, transient receptor potential cation channel subfamily M member 7 antibody, transient receptor potential cation channel, subfamily M, member 7 antibody, TRPM7 antibody, trpm7 antibody, Trpm7 antibody

Background: TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]

UniProt: Q96QT4