PPP2R5B antibody (C-Term)

Catalog No. ABIN497958

Product Details anti-PPP2R5B Antibody

Target: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Binding Specificity: AA 434-447, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5B antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Recognizes PPP2R5B (484-497).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 434-447 of PPP2R5B

Application Details

Application Notes: Western blotting: 1/500-1/3000. Positive Control: A431.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.55 mg/mL

Buffer: 1xPBS, 10 % Glycerol ( pH 7) and 0.01 % Thimerosal as preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C.

Target Details for PPP2R5B

Target: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Alternative Name: PPP2R5B (PPP2R5B Products)

Synonyms: B56B antibody, PR61B antibody, B'beta antibody, BC026670 antibody, PPP2R5B antibody, ppp2r5e antibody, protein phosphatase 2 regulatory subunit B'beta antibody, protein phosphatase 2, regulatory subunit B', beta antibody, protein phosphatase 2A regulatory subunit B' antibody, protein phosphatase 2 regulatory subunit B', beta antibody, protein phosphatase 2 regulatory subunit Bbeta antibody, PPP2R5B antibody, Ppp2r5b antibody, ppp2r5b antibody, ppp2r5b.L antibody, PPP2R2B antibody

Background: PPP2R5B belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily.Synonyms: PP2A B subunit B' beta isoform, PP2A B subunit B56 beta isoform, PR61 beta isoform, R5 beta isoform, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform, protein phosphatase 2A regulatory subunit B' beta

Molecular Weight: 57 kDa

Gene ID: 5526, 9606

UniProt: Q15173

Pathways: PI3K-Akt Signaling, ER-Nucleus Signaling