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IL2 Receptor beta antibody
IL2RB
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IL2 Receptor beta Antibody
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Target
See all IL2 Receptor beta (IL2RB) Antibodies
IL2 Receptor beta (IL2RB)
(Interleukin 2 Receptor, beta (IL2RB))
Reactivity
All reactivities for IL2 Receptor beta antibodies
Human
Host
All hosts for IL2 Receptor beta antibodies
Rabbit
Clonality
All clonalities for IL2 Receptor beta antibodies
Polyclonal
Conjugate
All conjugates for IL2 Receptor beta antibodies
This IL2 Receptor beta antibody is un-conjugated
Application
All applications for IL2 Receptor beta antibodies
Western Blotting (WB)
Specificity
This antibody detects endogenous levels of IL-2Rβ protein. (region surrounding Leu90)
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography using epitope-specific immunogen
Purity
> 95 % (by SDS-PAGE)
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Discover our top product IL2RB Primary Antibody
Alternatives
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Application Details
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Application Notes
Western blot: 1: 500 - 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Target Details for IL2 Receptor beta
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Target
IL2 Receptor beta (IL2RB)
(Interleukin 2 Receptor, beta (IL2RB))
Alternative Name
CD122 / IL2RB (IL2RB Products )
Synonyms
IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
Background
IL2 Receptor beta (CD122) is a member of the immunoglobulin superfamily that forms the high affinity IL2 receptor with CD25 and CD132. This receptor chain, which is also shared by the IL15 receptor, is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL2 Receptor beta chain can combine with either the common gamma subunit (gamma c) alone or the gamma c subunit and the IL2 Receptor alpha subunit to generate intermediate or high affinity IL2 receptor complexes, respectively. CD122 levels can be upregulated by activation stimuli such as IL2.Synonyms: IL-2 receptor subunit beta, IL2 Receptor beta, Interleukin-2 receptor subunit beta, P70-75
Molecular Weight
approx. 60 kDa
Gene ID
3560
NCBI Accession
NP_000869
UniProt
P14784
Pathways
JAK-STAT Signaling , Growth Factor Binding
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