×
For best experience we recommend to activate Javascript in your browser.
NPM1 antibody
NPM1
Reactivity: Human, Mouse, Rat
WB, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NPM1 Antibody
(hide)
Target
See all NPM1 Antibodies
NPM1
(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
Reactivity
All reactivities for NPM1 antibodies
Human, Mouse, Rat
Host
All hosts for NPM1 antibodies
Rabbit
Clonality
All clonalities for NPM1 antibodies
Polyclonal
Conjugate
All conjugates for NPM1 antibodies
This NPM1 antibody is un-conjugated
Application
All applications for NPM1 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects endogenous levels of NPM protein. (region surrounding Lys230)
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography
Purity
> 95 % by SDS-PAGE
Top Product
Discover our top product NPM1 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
(hide)
Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for NPM1
(hide)
Target
NPM1
(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
Alternative Name
Nucleophosmin (NPM1 Products )
Synonyms
B23 antibody, NPM antibody, NO38 antibody, Npm antibody, B23NP antibody, npm4 antibody, npm antibody, CG7917 antibody, CRP1 antibody, Crp1 antibody, Dmel\\CG7917 antibody, dNLP antibody, dNLP-S antibody, p22 antibody, npm1 antibody, sb:cb487 antibody, nucleophosmin 1 antibody, nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog antibody, nucleophosmin 1b antibody, Nucleophosmin antibody, nucleophosmin antibody, nucleophosmin (nucleolar phosphoprotein B23, numatrin) antibody, Nucleoplasmin antibody, nucleophosmin 1a antibody, NPM1 antibody, Npm1 antibody, npm1.L antibody, npm1b antibody, npm antibody, Nlp antibody, npm1a antibody
Background
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.Synonyms: NPM, NPM1, Nucleolar Phosphoprotein B23, Nucleolar Protein NO38, Numatrin
Molecular Weight
approx. 33 kDa
Gene ID
4869
NCBI Accession
NP_002511
UniProt
P06748
Pathways
Ribonucleoprotein Complex Subunit Organization , Ribosome Assembly
Recently viewed
(hide)