MRPS22 antibody

Catalog No. ABIN498971

Product Details anti-MRPS22 Antibody

Target: MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS22 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of MRPS22 protein. (region surrounding Arg263)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MRPS22

Target: MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))

Alternative Name: MRPS22 (MRPS22 Products)

Synonyms: AAF56757 antibody, CG12261 antibody, Dmel\\CG12261 antibody, MRP-S22 antibody, MrpS22 antibody, C3orf5 antibody, COXPD5 antibody, GIBT antibody, RPMS22 antibody, 3100002P07Rik antibody, Rpms22 antibody, DKFZp468F2212 antibody, zgc:165596 antibody, mitochondrial ribosomal protein S22 antibody, 28S ribosomal protein S22, mitochondrial antibody, mRpS22 antibody, MRPS22 antibody, Mrps22 antibody, LOC726000 antibody, mrps22 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR, both transcripts encode the same protein.Synonyms: 28S ribosomal protein S22, C3orf5, GK002, RPMS22, S22mt, mitochondrial

Molecular Weight: approx. 41 kDa

Gene ID: 56945

NCBI Accession: NP_064576

UniProt: P82650