MRPS34 antibody

Catalog No. ABIN498973

Product Details anti-MRPS34 Antibody

Target: MRPS34 (Mitochondrial Ribosomal Protein S34 (MRPS34))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS34 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of MRPS34 protein. (region surrounding Lys214)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MRPS34

Target: MRPS34 (Mitochondrial Ribosomal Protein S34 (MRPS34))

Alternative Name: MRPS34 (MRPS34 Products)

Synonyms: MRP-S12 antibody, MRP-S34 antibody, MRPS12 antibody, CG13037 antibody, CG42648 antibody, Dmel\\CG42648 antibody, Dmel_CG13037 antibody, 0610007F04Rik antibody, 5330430D13Rik antibody, AV001970 antibody, Tce2 antibody, MGC53021 antibody, MGC89027 antibody, fa19c10 antibody, wu:fa19c10 antibody, zgc:101877 antibody, mitochondrial ribosomal protein S34 antibody, mitochondrial ribosomal protein S34 S homeolog antibody, uncharacterized LOC408493 antibody, MRPS34 antibody, mRpS34 antibody, Mrps34 antibody, mrps34.S antibody, LOC408493 antibody, mrps34 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR, both transcripts encode the same protein.Synonyms: 28S ribosomal protein S34, MRP-S34, S34mt, mitochondrial

Molecular Weight: approx. 26 kDa

Gene ID: 65993

NCBI Accession: NP_076425

UniProt: P82930