CSPG5 antibody

Catalog No. ABIN499046

Product Details anti-CSPG5 Antibody

Target: CSPG5 (Chondroitin Sulfate Proteoglycan 5 (Neuroglycan C) (CSPG5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSPG5 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of Neuroglycan C protein. (region surrounding Trp248)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CSPG5

Target: CSPG5 (Chondroitin Sulfate Proteoglycan 5 (Neuroglycan C) (CSPG5))

Alternative Name: Neuroglycan C (CSPG5 Products)

Synonyms: CSPG5 antibody, cspg5 antibody, si:dkeyp-114f9.4 antibody, Caleb antibody, Ngc antibody, NGC antibody, CALEB antibody, chondroitin sulfate proteoglycan 5 antibody, chondroitin sulfate proteoglycan 5a antibody, chondroitin sulfate proteoglycan 5b antibody, CSPG5 antibody, cspg5a antibody, cspg5b antibody, Cspg5 antibody

Background: Neuroglycan C is a transmembrane chondroitin sulfate proteoglycan that is exclusively expressed in the central nervous system. NGC gene expression is developmentally regulated being altered by addiction to psychostimulants and by nerve lesion. Its core protein has a particular multidomain structure differing from those of other known proteoglycans, and this protein is modified post-translationally in various ways such as phosphorylation and glycosylation. Neuroglycan C is a novel part-time proteoglycan that changes its structure from a proteoglycan form to a non-proteoglycan form without chondroitin sulfate chains during the development of the cerebellum and retina. Evidence suggests that Neuroglycan C is involved in neuronal circuit formation in the central nervous system.Synonyms: Acidic leucine-rich EGF-like domain-containing brain protein, CALEB, CSPG5, Chondroitin sulfate proteoglycan 5, NGC

Molecular Weight: approx. 60 kDa

Gene ID: 10675

NCBI Accession: NP_006565

UniProt: O95196

Pathways: Glycosaminoglycan Metabolic Process