GABRD antibody
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- Target See all GABRD Antibodies
- GABRD (GABA A Receptor delta (GABRD))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GABRD antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects endogenous levels of GABAA Rδ protein. (region surrounding Asp181)
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity chromatography using epitope-specific immunogen
- Purity
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product GABRD Primary Antibody
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- Application Notes
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- GABRD (GABA A Receptor delta (GABRD))
- Alternative Name
- GABRD (GABRD Products)
- Synonyms
- GABRD antibody, EIG10 antibody, EJM7 antibody, GEFSP5 antibody, GABAA-RD antibody, AI853201 antibody, gamma-aminobutyric acid type A receptor delta subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit delta antibody, GABRD antibody, Gabrd antibody
- Background
- GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (γ-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA Rrho1 and GABAA Rrho2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.Synonyms: GABA A receptor subunit delta, Gamma-aminobutyric acid receptor subunit delta
- Molecular Weight
- approx. 51 kDa
- Gene ID
- 2563
- NCBI Accession
- NP_000806
- UniProt
- O14764
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