CTRP5 antibody (N-Term)

Catalog No. ABIN499673

Product Details anti-CTRP5 Antibody

Target: CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))

Binding Specificity: N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTRP5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: CTRP5 antibody was raised against a 15 amino acid peptide from near the amino terminus of human CTRP5.

Purification: Affinity chromatography purified via peptide column

Immunogen: Murine CTRP5 (N-Terminus) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: CTRP5 antibody can be used for the detection of CTRP5 at 1 - 2 μg/mL. Humanbrain cell lysate can be used as positive control. These proteins are often highly modifiedpost-translationally and migrate in SDS-PAGE at positions other than their predicted size. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CTRP5

Target: CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))

Alternative Name: C1QTNF5 (C1QTNF5 Products)

Synonyms: C1QTNF5 antibody, wu:fb02c10 antibody, wu:fb02f05 antibody, zgc:112378 antibody, CTRP5 antibody, Ctrp5 antibody, C1q and tumor necrosis factor related protein 5 antibody, C1q and TNF related 5 antibody, C1QTNF5 antibody, c1qtnf5 antibody, C1qtnf5 antibody

Background: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). CTRP5 has been suggested to be involved in age-related macular degeneration (5).Synonyms: CTRP5, Complement C1q tumor necrosis factor-related protein 5

Gene ID: 114902

UniProt: Q9BXJ0