ELISA. Western Blot: CTRP7 antibody can be used for the detection of CTRP7 at 0.5 μg/mL.3T3 celllysate can be used as positive control. These proteins often migrate in SDS-PAGE atpositions other than their predicted size. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C.
Target
CTRP7 (C1QTNF7)
(C1q and Tumor Necrosis Factor Related Protein 7 (C1QTNF7))
C1QTNF7 antibody, 5530401N20Rik antibody, 8430425G24Rik antibody, Ctrp7 antibody, CTRP7 antibody, ZACRP7 antibody, C1q and tumor necrosis factor related protein 7 antibody, C1q and TNF related 7 antibody, C1QTNF7 antibody, C1qtnf7 antibody
Background
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Like the other members of the adiponectin and CTRP protein family, the mature CTRP7 is secreted and can be found in the organismSynonyms: CTRP7, Complement C1q tumor necrosis factor-related protein 7, ZACRP7