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ECAT1 antibody (AA 1-100) (Alexa Fluor 750)

KHDC3L Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 750
Catalog No. ABIN5001705
  • Target See all ECAT1 (KHDC3L) Antibodies
    ECAT1 (KHDC3L) (KH Domain Containing 3-Like, Subcortical Maternal Complex Member (KHDC3L))
    Binding Specificity
    • 14
    • 8
    • 8
    • 7
    AA 1-100
    Reactivity
    Human
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ECAT1 antibody is conjugated to Alexa Fluor 750
    Application
    • 16
    • 16
    • 14
    • 14
    • 12
    • 12
    • 6
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Ecat1
    Isotype
    IgG
    Top Product
    Discover our top product KHDC3L Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ECAT1 (KHDC3L) (KH Domain Containing 3-Like, Subcortical Maternal Complex Member (KHDC3L))
    Alternative Name
    Ecat1 (KHDC3L Products)
    Synonyms
    C6orf221 antibody, ECAT1 antibody, HYDM2 antibody, KH domain containing 3 like, subcortical maternal complex member antibody, KHDC3L antibody
    Background

    Synonyms: C6orf221, Chromosome 6 open reading frame 221, ES cell-associated transcript 1 protein, HYDM2, KHD3L_HUMAN, KHDC3-like protein, KHDC3L.

    Background: ECAT1 (ES cell-associated transcript 1 protein) is a 217 amino acid protein that belongs to the KHDC1 family. The ECAT1 protein contains an atypical KH domain with amino acid changes at critical sites, suggesting that it may not bind RNA. Expression of ECAT1 appears to be maximal in germinal vesicle oocytes, it tails off through metaphase II oocytes and is undetectable following the completion of the oocyte to embryo transition. Specifically expressed in the oocytes, recent studies suggest that ECAT1 may function as a regulator of genomic imprinting in the oocyte. Defects in ECAT1 are the cause of hydatidiform mole recurrent type 2 (HYDM2), a disorder characterized by excessive trophoblast development that produces a growing mass of tissue inside the uterus at the beginning of a pregnancy. HYDM2 leads to abnormal pregnancies with no embryo, and cystic degeneration of the chorionic villi.

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