Hepsin antibody (AA 311-417) (Alexa Fluor 750)

Catalog No. ABIN5004485

Product Details anti-Hepsin Antibody (Alexa Fluor 750)

Target: Hepsin (HPN)

Binding Specificity: AA 311-417

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hepsin antibody is conjugated to Alexa Fluor 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Hepsin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Hepsin

Target: Hepsin (HPN)

Alternative Name: Hepsin (HPN Products)

Synonyms: TMPRSS1 antibody, Hlb320 antibody, hepsin antibody, si:dkey-33i11.3 antibody, HPN antibody, si:dkey-33i11.3 antibody, Hpn antibody

Background:

Synonyms: HEPS, HEPS_HUMAN, Hepsin, HPN, Serine protease hepsin, Serine protease hepsin catalytic chain, Serine protease hepsin non catalytic chain, TMPRSS 1, TMPRSS1, Transmembrane protease serine 1.

Background: This gene encodes a type II transmembrane serine protease. The encoded protein has an extracellular region that consists of two domains, a catalytic serine protease domain and a non-catalytic scavenger receptor cysteine-rich domain. This protein may be involved in diverse cellular functions including blood coagulation, maintenance of cell morphology and the growth and progression of certain cancers, particularly prostate cancer. Alternative splicing results in multiple transcript variants.

Gene ID: 3249

Pathways: Regulation of Hormone Metabolic Process, Sensory Perception of Sound