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Chromosome 11open Reading Frame 9 (C11orf9) (AA 401-500) antibody (Alexa Fluor 750)

C11orf9 Reactivity: Human, Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 750
Catalog No. ABIN5007241
  • Target See all Chromosome 11open Reading Frame 9 (C11orf9) Antibodies
    Chromosome 11open Reading Frame 9 (C11orf9)
    Binding Specificity
    • 14
    • 6
    • 3
    • 2
    • 1
    • 1
    AA 401-500
    Reactivity
    • 23
    • 21
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 27
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Alexa Fluor 750
    Application
    • 21
    • 12
    • 12
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MYRF
    Isotype
    IgG
    Top Product
    Discover our top product C11orf9 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Chromosome 11open Reading Frame 9 (C11orf9)
    Alternative Name
    MYRF/C11orf9 (C11orf9 Products)
    Synonyms
    C11orf9 antibody, c11orf9 antibody, mrf antibody, ndt80 antibody, MRF antibody, Ndt80 antibody, pqn-47 antibody, 6030439E18 antibody, Gm1804 antibody, Gm98 antibody, Mrf antibody, chromosome 5 open reading frame, human C11orf9 antibody, myelin regulatory factor L homeolog antibody, myelin regulatory factor antibody, C5H11ORF9 antibody, myrf.L antibody, MYRF antibody, Myrf antibody
    Background

    Synonyms: MRF, Ndt80, pqn-47, C11orf9, Myelin regulatory factor, Myelin gene regulatory factor, MYRF, KIAA0954

    Background: Myelin regulatory factor: Consitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype (PubMed:23966832).

    Gene ID
    745
    UniProt
    Q9Y2G1
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