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PCDHB12 antibody (AA 121-220) (Alexa Fluor 680)

PCDHB12 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 680
Catalog No. ABIN5008439
  • Target See all PCDHB12 Antibodies
    PCDHB12 (Protocadherin beta 12 (PCDHB12))
    Binding Specificity
    • 14
    • 8
    • 8
    • 7
    • 2
    • 1
    AA 121-220
    Reactivity
    • 40
    • 1
    Human
    Host
    • 36
    • 4
    Rabbit
    Clonality
    • 36
    • 4
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PCDHB12 antibody is conjugated to Alexa Fluor 680
    Application
    • 40
    • 21
    • 13
    • 12
    • 12
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PCDHB12
    Isotype
    IgG
    Top Product
    Discover our top product PCDHB12 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PCDHB12 (Protocadherin beta 12 (PCDHB12))
    Alternative Name
    PCDHB12 (PCDHB12 Products)
    Synonyms
    PCDH-BETA12 antibody, Pcdh3 antibody, Pcdhb5F antibody, PcdhbL antibody, PCDHB12 antibody, PCDHB10 antibody, PCDHB13 antibody, protocadherin beta 12 antibody, protocadherin beta-12 antibody, PCDHB12 antibody, Pcdhb12 antibody, LOC515337 antibody, LOC100452074 antibody
    Background

    Synonyms: PCDH beta12, PCDHB 12, PCDHB12, PCDBC_HUMAN.

    Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains. PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain.

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