PILRB antibody (AA 51-150) (Alexa Fluor 680)

Catalog No. ABIN5008845

Product Details anti-PILRB Antibody (Alexa Fluor 680)

Target: PILRB (Paired Immunoglobin-Like Type 2 Receptor beta (PILRB))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PILRB antibody is conjugated to Alexa Fluor 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse PILR beta

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PILRB

Target: PILRB (Paired Immunoglobin-Like Type 2 Receptor beta (PILRB))

Alternative Name: PILR beta (PILRB Products)

Background:

Synonyms: Paired immunoglobulin-like type 2 receptor beta, Activating receptor PILR beta, Cell surface receptor FDFACT, Cell surface receptor FDFACT1, Cell surface receptor FDFACT2, FDFACT, FDFACT1, FDFACT2, PILR_, Paired immunoglobulin like receptor beta, Paired immunoglobulin like type 2 receptor beta, Paired immunoglobulin like type 2 receptor beta precursor.

Background: Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing.

Gene ID: 170741