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SORCS2 antibody (AA 201-300) (Alexa Fluor 750)

SORCS2 Reactivity: Human WB, IF (p), IF (cc) Host: Rabbit Polyclonal Alexa Fluor 750
Catalog No. ABIN5010850
  • Target See all SORCS2 Antibodies
    SORCS2 (Sortilin-Related VPS10 Domain Containing Receptor 2 (SORCS2))
    Binding Specificity
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 201-300
    Reactivity
    • 26
    • 2
    • 2
    Human
    Host
    • 23
    • 3
    • 1
    Rabbit
    Clonality
    • 25
    • 2
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SORCS2 antibody is conjugated to Alexa Fluor 750
    Application
    • 22
    • 13
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SORCS2
    Isotype
    IgG
    Top Product
    Discover our top product SORCS2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SORCS2 (Sortilin-Related VPS10 Domain Containing Receptor 2 (SORCS2))
    Alternative Name
    SORCS2 (SORCS2 Products)
    Synonyms
    SORCS2 antibody, N28137 antibody, mKIAA1329 antibody, sortilin related VPS10 domain containing receptor 2 antibody, VPS10 domain-containing receptor SorCS2 antibody, sortilin-related VPS10 domain containing receptor 2 antibody, SORCS2 antibody, LOC100467197 antibody, sorcs2 antibody, Sorcs2 antibody
    Background

    Synonyms: KIAA1329, SORCS 2, Sortilin related VPS10 domain containing receptor 2, VPS10 domain receptor protein, VPS10 domain receptor protein SORCS 2, SORC2_HUMAN.

    Background: There are three SorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, SorCS1, SorCS2 and SorCS3 genes are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS2 (sortilin-related VPS10 domain containing receptor 2) is a 1,150 amino acid single-pass type I membrane protein that is highly expressed in brain and kidney. Containing six BNR repeats and a single PKD domain, SorCS2 is encoded by a gene that maps to human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.

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