Stabilin 1 antibody (Alexa Fluor 750)

Catalog No. ABIN5011029

Product Details anti-Stabilin 1 Antibody (Alexa Fluor 750)

Target: Stabilin 1 (STAB1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stabilin 1 antibody is conjugated to Alexa Fluor 750

Application: Western Blotting (WB)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human stabilin1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Stabilin 1

Target: Stabilin 1 (STAB1)

Alternative Name: stabilin1 (STAB1 Products)

Background:

Synonyms: CLEVER 1, Common lymphatic endothelial and vascular endothelial receptor 1, Fasciclin EGF like laminin type EGF like and link domain containing scavenger receptor 1, fasciclin egf-like, FEEL 1, FELE 1, FEX1, KIAA0246, MS 1 antigen, STAB1, STAB-1, STAB 1, STAB1_HUMAN.

Background: Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes.

Gene ID: 23166