AP3D1 antibody (AA 400-680)

Catalog No. ABIN5027027

Product Details anti-AP3D1 Antibody

Target: AP3D1 (Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1))

Binding Specificity: AA 400-680

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3D1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant AP3 Delta protein (amino acids 400-680) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 2-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for AP3D1

Target: AP3D1 (Adaptor-Related Protein Complex 3, delta 1 Subunit (AP3D1))

Alternative Name: AP3 Delta (AP3D1 Products)

Synonyms: wu:fj51g01 antibody, si:ch211-129c21.6 antibody, ADTD antibody, hBLVR antibody, AA407035 antibody, Ap3d antibody, Bolvr antibody, mBLVR1 antibody, mh antibody, mocha antibody, BLVR antibody, adaptor-related protein complex 3, delta 1 subunit antibody, AP-3 complex subunit delta-1 antibody, adaptor related protein complex 3 delta 1 subunit antibody, ap3d1 antibody, EDI_172030 antibody, EHI_158840 antibody, Tsp_04773 antibody, AP3D1 antibody, Ap3d1 antibody

Background: AP3D1 (AP-3 complex subunit delta-1) encodes the delta 1 subunit of an adaptor protein regulating intracellular vesicle-mediated transport (19631730). Lack of expression of functional AP-3, leads to a deficiency in vesicle transport and storage, which affects neurotransmitter vesicle turnover and release in the central nervous system (19032734). The AP-3 complex facilitates the budding of vesicles from the golgi membrane, and directly involved in trafficking to lysosomes. It is implicated in intracellular biogenesis and trafficking of pigment granules and possibly platelet dense granules and neurotransmitter vesicles.

Molecular Weight: 122 kDa

Gene ID: 8943

UniProt: O14617