ASAP3 antibody (AA 550-800)

Catalog No. ABIN5027045

Product Details anti-ASAP3 Antibody

Target: ASAP3 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3))

Binding Specificity: AA 550-800

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASAP3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogen: A partial length recombinant ASAP3 protein (amino acids 550-800) was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: WB: 2-4 μg/mL This antibody detects ~43 kDa band. The size corresponds to Isoform 2 (Uniprot ID-Q8TDY4-2) of ASAP3, the right size is ~99 kDa.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for ASAP3

Target: ASAP3 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 3 (ASAP3))

Alternative Name: ASAP3 (ASAP3 Products)

Synonyms: DDEFL1 antibody, ddefl1 antibody, zgc:113885 antibody, ACAP4 antibody, CENTB6 antibody, UPLC1 antibody, 9430088F20Rik antibody, Ddefl1 antibody, Gm140 antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 antibody, development and differentiation enhancing factor-like 1 antibody, ASAP3 antibody, asap3 antibody, DDEFL1 antibody, Asap3 antibody

Background: ASAP3 belongs to Arf-specific GTPase-activating proteins which regulate Arfs by stimulating their intrinsic GTP hydrolysis. This protein contains a catalytic core of a PH (Pleckstrin Homology) domain, a GAP motif, and two ANK (Ankyrin) repeats. ASAP3 also associates with focal adhesions and with cytoplasmic membranes at the circular dorsal ruffles, where the actin skeleton is remodeled. Depletion of ASAP3 by RNA interference suppresses cell migration in wound healing.

Molecular Weight: 43 kDa (Isoform)

Gene ID: 55616

UniProt: Q8TDY4